Cambridge (CIE) IGCSE Biology

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(Diseases and Immunity)

Active Immunity, Antigens & Antibodies

Your Body’s Clever Warriors: Active Immunity, Antigens & Antibodies

 

What Is Active Immunity?

Active immunity is when your body makes its own special defenders (antibodies) after it encounters a pathogen (germ). Once your body learns how to fight it off, it remembers, so if that same germ tries to attack again, your body is ready to protect you!

Think of it like learning to ride a bike: once you know how, you don’t forget.

 

Antigens: The “Name Tags” of Pathogens

Every pathogen has unique antigens on its surface—like tiny name tags with special shapes. Different pathogens have different-shaped antigens, so your body can tell them apart.

 

Antibodies: The Perfect “Locks and Keys”

Your body’s immune system makes antibodies, which are like tiny “locks” that perfectly fit the “keys” (antigens) on a germ. When antibodies attach to these antigens:

  1. They can help destroy the pathogen directly.
  2. Or they can mark it, so other cells know to come and gobble it up.

Key idea: Each antibody fits only one type of antigen, just like a key that opens only one lock.

 

Putting It All Together

  1. A pathogen enters your body.
  2. Your immune system spots the pathogen’s antigens.
  3. Special cells produce the perfect matching antibodies.
  4. The antibodies bind to the antigens and help defeat the pathogen.
  5. Your body remembers how to make those antibodies for next time, giving you active immunity.

 

 

Tuity Tip

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Antigen = “Name tag” on a pathogen.

Antibody = Special “lock” that fits the pathogen’s “key” (antigen).

Active immunity = Your body learns and remembers, giving long-term protection.

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